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Friday, July 31, 2020 | History

2 edition of Effects of 2,4-dinitrophenol on respiratory metabolism in the coleoptile of Zea mays L. found in the catalog.

Effects of 2,4-dinitrophenol on respiratory metabolism in the coleoptile of Zea mays L.

Kin-Wah Cheung

Effects of 2,4-dinitrophenol on respiratory metabolism in the coleoptile of Zea mays L.

by Kin-Wah Cheung

  • 8 Want to read
  • 35 Currently reading

Published in [Toronto] .
Written in English

    Subjects:
  • Corn.,
  • Plants -- Respiration,
  • Plants -- Metabolism,
  • Dinitrophenol

  • Edition Notes

    Botany theses

    ContributionsToronto, Ont. University. Theses (M.Sc.)
    Classifications
    LC ClassificationsLE3 T525 MSC 1966 C548
    The Physical Object
    Pagination[56 leaves]
    Number of Pages56
    ID Numbers
    Open LibraryOL15162654M

    Oct 27,  · There have been reports of misuse of 2,4-Dinitrophenol by anorexic and bulimic individuals and in intentional overdoses. The use of high doses as a dieting aid has been associated with severe side-effects, including death. 2,4-Dinitrophenol is rapidly absorbed through the gastrointestinal tract, respiratory tract and intact skin. Dinitrophenol (DNP) is a chemical used in the manufacture of explosives, herbicides, dyes, and wood preservatives. When, in , a researcher a Stanford University discovered that ingestion of DNP caused to rapid weight loss, the chemical became available without prescription in a number of over-the-counter diet aids.

    Effect of 2,4-dinitrophenol on Krebs cycle and phosphate metabolism in baker's yeast cycle as shown by the opposite effects of 2,4-dinitrophenol and glucose. book reviews experimental. Any research on safe dosage for use of 2,4-Dinitrophenol in humans? I have been lurking around the internet, but all I've been finding is anecdotal evidence. One guy writing that you should X dose, another saying that you use Y dose.

    The effect of 2,4‐dinitrophenol on electrical and mechanical activity, metabolism and ion movements in guinea‐pig ventricular muscle. T. F. McDONALD. Department of Physiology and Biophysics, Dalhousie University, Halifax, Nova flatmountaingirls.com by: The ATSDR toxicological profile succinctly characterizes the toxicologic and adverse health effects information for these toxic substances described therein.


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Effects of 2,4-dinitrophenol on respiratory metabolism in the coleoptile of Zea mays L by Kin-Wah Cheung Download PDF EPUB FB2

The 2,4-Dinitrophenol (DNP) is a highly toxic yet highly effective solution for weight loss. The primary function of DNP is to increase heat production in the body cells to make them less efficient with energy.

Although DNP has yielded proven results when it comes to weight loss, even small overdoses have been reported to result in death. 2,4-Dinitrophenol is considered to have high acute toxicity, based on short-term animal tests in rats and mice.

(3) Chronic Effects (Noncancer): Chronic oral exposure to 2,4-dinitrophenol in humans and animals has resulted in the formation of cataracts and skin lesions and has caused effects on the bone marrow, CNS, and cardiovascular system. (1,2). Respiration Physiology () 57, 1 Elsevier EFFECTS OF INCREASING METABOLISM BY 2,4-DINITROPHENOL ON RESPIRATION AND PULMONARY GAS EXCHANGE IN THE DUCK J.

GEISER*, R.K. GRATZ*, T. HIRAMOTO* and P. SCHEID Abteilung Physiologie, Max-Planck-lnstitut fiir experimentelle Medizin, D G6ttingen, and lnstitut fiir Physiologie, flatmountaingirls.com by: Jul 08,  · 2,4-Dinitrophenol (DNP) is reported to cause rapid loss of weight, but unfortunately is associated with an unacceptably high rate of significant adverse effects.

DNP is sold mostly over the internet under a number of different names as a weight loss/slimming flatmountaingirls.com by: 2,4-Dinitrophenol elevates the BMR, lowers the serum T4 concentration, accelerates the peripheral metabolism of T4, and depresses thyroidal RAIU and secretion.

Its actions are probably complex. Like T4, the drug stimulates metabolism by uncoupling oxidative. 2,4-Dinitrophenol (2,4-DNP or simply DNP) is an organic compound with the formula HOC 6 H 3 (NO 2) 2. It is a yellow, crystalline solid that has a sweet, musty odor. It sublimes, is volatile with steam, and is soluble in most organic solvents as well as aqueous alkaline flatmountaingirls.comg point: °C ( °F; K).

Effects of salicylate and 2,4-dinitrophenol on respiration and metabolism. Millhorn DE, Eldridge FL, Waldrop TG. The respiratory and metabolic responses to intravenous administration of sodium salicylate ( mg/kg) and 2,4-dinitrophenol ( mg/kg), uncouplers of oxidative phosphorylation, were studied in anesthetized, paralyzed Cited by: You are now following 2,4-Dinitrophenol.

You will be notified when any significant update is made. flatmountaingirls.com and its Editors do not ensure that unforeseen side effects will not occur even at the proper dosages, and thereby does not assume liability for any side effects from supplements or practices hosted under the domain of flatmountaingirls.com Oct 01,  · 2,4-Dinitrophenol (DNP), an uncoupler of oxidative phosphorylation, has been frequently used to evaluate the effects of energy depletion on methotrexate (MTX) transport.

The results from these studies, however, have shown a multiplicity of effects that suggest a more complicated interaction with the MTX transport system than adenosine 5′-triphosphate depletion alone. Accordingly, studies. Saiki, Chikako, and Jacopo P. Mortola. Effect of 2,4-dinitrophenol on the hypometabolic response to hypoxia of conscious adult rats.

Appl. Physiol. 83(2): –, —During acute hypoxia, a hypometabolic response is commonly observed in many newborn and adult mammalian species. We hypothesized that, if hypoxic hypometabolism were entirely a regulated response with no limitation in Cited by: The Mechanism of Uncoupling of Oxidative Phosphorylation by 2,4=Dinitrophenol* (Received for publication, January 18, ) GIFFORD B.

PINCHOT$ From the McC’ollum-Pratt Institute and Depadment of Biology, The Johns Hopkins University, Baltimore, Maryland dlWi8 SUMMARY. Start studying etc solutions. Learn vocabulary, terms, and more with flashcards, games, and other study tools. Search. The observed effects are consistent with the action of an uncoupler—that is, an If a solution of 2,4-dinitrophenol is now added to the preparation, O2 consumption returns to normal but ATP production remains inhibited.

A COMPARISON OF THE INFLUENCE OF 2,4-DINITROPHENOL ON THE OXYGEN CONSUMPTION OF RAT BRAIN SLICES AND HOMOGENATES* BY CLARENCE NORMAN I’EISS AND JOHN FIELD (From the Departmen.t of Physiology, Stanford University School of Medicine, Stanford University, Californian) (Received for publication, March 17, ).

Well, apart from the need for more experiments, let alone the requirement to carry out several stages of trials in humans, 2,4-dinitrophenol (DNP) is a dangerous chemical with a chequered past.

How is that. Like picric acid (2,4 6-trinitrophenol), 2, 4-dinitrophenol is a powerful explosive material. A) The substrate will be oxidized until the addition of the 2,4-dinitrophenol, which blocks further oxidation.

B) There is no effect; oxidation of the substrate continues at the same rate before and after the addition of 2,4-dinitrophenol.

C) The substrate cannot be oxidized. 1A technique has been developed for studying over periods of 10 min or longer the effects of drugs on both the force of electrically‐induced contractions and the oxygen consumption of an isolated, curarized.

The effect of 2, 4-dinitrophenol upon frog heart metabolism and function. Imprint Physical description 26 numb. mounted plates, diagrs. Online. Available online At the library. SAL1&2 (on-campus shelving) Stacks Request.

Items in Stacks; Call number Status; S78L. Light produces no effect on the resistance to 2,4-dinitrophenol of protoplasmic streaming in scale cells of Allium cepa L. bulbs, nor in the sensitivity of ciliated epithelium movement in the. May 06,  · The warning concerns “2,4-dinitrophenol” (DNP), a combination of compounds that increases body temperature and metabolic rate.

Last month a. Metabolism Problem Set Problem 4: Dinitrophenol Correct. Dinitrophenol (DNP) is an uncoupler, or has the ability to separate the flow of electrons and the pumping of H + ions for ATP synthesis.

This means that the energy from electron transfer cannot be used for ATP synthesis. EPA R June Update of Human Health Ambient Water Quality Criteria: 2,4-Dinitrophenol Office of Science and Technology Office of Water.Jul 08,  · 2,4-Dinitrophenol (DNP) is reported to cause rapid loss of weight, but unfortunately is associated with an unacceptably high rate of significant adverse effects.

DNP is sold mostly over the internet under a number of different names as a weight loss/slimming aid. It causes uncoupling of oxidative phosphorylation; the classic symptom complex associated with toxicity of phenol-based Cited by: The effects of varying concentrations of 2,4-dinitrophenol on the oxidation of a series of saturated, aliphatic fatty acids byPs.

aeruginosa were studied. The oxidation of C 4, C 6, C 8, C 10, C 12, C 13, C 14 and C 16 acids is stimulated by certain concentrations of this inhibitor. However, the concentration of 2,4-dinitrophenol which causes stimulation of oxygen uptake with capric acid does Author: R.

H. Bauerle, E. O. Bennett.